
The temporary relief of symptoms associated with seasonal and perennial allergic and non-allergic rhinitis, and sinusitis. Chlorpheniramine Maleate temporarily relieves runny nose and reduces sneezing, itching of the nose or throat, and itchy, watery eyes due to hay fever or other upper respiratory allergies. Scopolamine Methyl Nitrate further augments the anti-secretory activity of this product.
Chlorpheniramine Maleate competitively antagonizes most of the smooth muscle stimulating actions of histamine on the H1 receptors of the GI tract, uterus, large blood vessels, and bronchial muscle. It also antagonizes the action of histamine that results in increased capillary permeability and the formation of edema. Chlorpheniramine maleate is an alkylamine-type antihistamine. This group of antihistamines are among the most active histamine antagonists and are generally effective in relatively low doses. They thereby prevent, but do not reverse, responses mediated by histamine alone. The anticholinergic actions of most antihistamines provide a drying effect on the nasal mucosa.These drugs are not so prone to produce drowsiness and are among the most suitable agents for daytime use, but a significant proportion of patients do experience this effect. Scopolamine Methyl Nitrate is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids that exhibits antisecretory activity. Scopolamine methyl nitrate inhibits the muscarinic actions of acetylcholine on structures
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Adults and children 12 years of age and older: 1 teaspoonful (5 mL) every 4 to 6 hours, not to exceed 6 teaspoonfuls in 24 hours. Children 6 to under 12 years of age: ½ teaspoonful (2.5 mL) every 4 to 6 hours, not to exceed 3 teaspoonfuls in 24 hours. RYNEZE LIQUID is not recommended for children under 6 years of age.
RYNEZE LIQUID is supplied as a clear, grape-flavored liquid, dye free, sugar free, alcohol free, and gluten free in 16 fl oz (473 mL) bottles, NDC 24839-346-16, and 10 mL sample, NDC 24839-346-10 |



